Skip to content

Podcast, News & Publications

Oak Tree

Peace in strength.  Like the mighty oak that has survived some 600 years in what is now my back yard, we engage with experience and resilience.  Whether the winds blow hard or the sun shines bright, we go on, deeply rooted and stretching for the heavens.

Strength in peace.  Many challenges of the world, and Pharmaceutical R&D, grow out of mere misunderstandings.  We seek to enhance mutual understanding and peaceful cooperation toward shared objectives.

- Peace and Strength by Kevin Freiert

Salem Oaks Presents: a podcast sharing the human stories behind the medicines

004 Donald Kirsch: Getting to Know a Drug Hunter

Dec 10, 2019

We’ve all been there. You are at a party and someone asks, “So, what do you do?” Dr. Kirsch always found it hard to explain his career as a discovery scientist. He decided to write a book about it.  The Drug Hunters: An Improbable Quest to Discover New Medicines is a colorful, fact-filled narrative history of…

Read More

Episode 3: Hope Can Be Curative.

Nov 18, 2019

David Pearce Ph.D., Sanford Research Leader Today we hear from David Pearce, PhD, President of Innovation and Research, Sanford Health and Vice Chair, Consortium Assembly, International Rare Disease Research Consortium (IRDiRC) Dr. Pearce’s rare disease background emanates from publishing over 100 research papers on Batten Disease. David talks to us about…

Read More

Episode 2: Kyle Bryant: Remember Why We Are Doing All This

Oct 9, 2019

We welcome Kyle Bryant of the Friedreich’s Ataxia Research Alliance (FARA) to discuss his journey as a patient with Friedreich’s Ataxia (FA), as an active patient leader, and in his job as a liaison between the FA community and researchers. After being diagnosed with FA when only 17 years old,…

Read More

Episode 1: David Fajgenbaum, MD, MBA, MSC, FCPP

Sep 25, 2019

Chasing My Cure: A Doctor’s Race to Turn Hope Into Action We are honored to have Dr. David Fajgenbaum as our first guest on Improbable Developments. His story is intense. Before he even earned is medical degree, he was faced by a rare life-threatening illness for which there was no…

Read More

Welcome to Improbable Developments!

Sep 1, 2019

In this, our first episode, Kevin lays out the objectives and plan for the Improbable Developments podcast. He also shares a personal story about a medicine he worked on earlier in his career.

Read More

News & Publications

Patient Engagement Strategies Lack Patient Voice, Consumer Input

By Kevin Freiert | Jan 30, 2018

I found this quite ironic.  “Physician, first heal thyself…” http://bit.ly/2Gv2Oj6

Read More

How many blessings can be squeezed into 20 years?

By Kevin Freiert | Jan 28, 2018

Twenty years ago, today, I woke up and had cancer. I had no idea what the day would bring.  It had been about two months since I was diagnosed with myxoid liposarcoma in my left thigh. 

Read More

Educating Patients: Taking Action to Refocus and Accelerate

By Kevin Freiert | Oct 30, 2017

Over the past weeks, I have discussed several barriers that make it difficult to involve patients in developing new medicines as much as everyone involved would like. My theory is that we need to do a better job educating patients.  I’d love to hear your thoughts on this topic. Some of these barriers…

Read More

Are We on the Right Track?

By Kevin Freiert | Oct 16, 2017

Choices. Have you ever found yourself in an unfamiliar city trying to get from point A to point B as quickly as possible?  Taxi? Bus? Subway? Traffic scares you, so the subway it is. You stare at the nicely designed kaleidoscope of a map and try to make sense of which…

Read More

No One is Truly Objective

By Kevin Freiert | Oct 9, 2017

As the winter approaches here in New England, the picture above caught my eye. What do you see? Is the sun setting… or rising? What’s up? What’s down? Where was the picture taken? When? How can you be sure? Did my opening line influence you? Introduction There seems to be a consensus from all…

Read More

Fellow Travelers on a Long, Cold Road

By Kevin Freiert | Oct 2, 2017

The journey to a new medicine is a challenging, uphill, and winding road. Whenever a patient gets involved in medicines development, they are likely to face a roller coaster of hopefulness and despair like they have never experienced. Since only about 5% of the compounds and proteins put into advanced testing a…

Read More

Leveling the Playing Field

By Kevin Freiert | Sep 25, 2017

“A champion named Goliath…came out from the Philistine camp. He was over nine feet tall. He had a bronze helmet on his head and wore a coat of scale armor of bronze weighing [125 pounds]; on his legs he wore bronze greaves, and a bronze javelin was slung on his back. His…

Read More

The Language of Drug Development

By Kevin Freiert | Sep 18, 2017

Let’s do a quick word association exercise. What is the first word that comes to mind when you read each of the terms below? Trial Investigator Subject Attrition Arms Targets Chances are your responses were somehow affected by your level of familiarity with medicines development. Introduction Patients are the most important…

Read More